Fueling the Viral Fire With mRNA

John Catanzaro
2 min readJan 2, 2021

2021 John A. Catanzaro, CEO of Neo7Logix

In the next few months to years, the existing trend of mRNA vaccines will reveal the shortfalls associated with their current designs. Currently, greater than 60% of the population affected by the COVID global outbreak are refusing the mRNA-based vaccines over concerns of safety and long-term adverse health effects.

RNA viruses are like parasites, and their replication requires host cell functions. mRNA degrades in an accelerated manner when introduced into the infected host cell. It is also subject to rapid decay and unpredictable by nature of its biogenesis. Therefore, mRNA is extremely difficult and unreliable for assuring vaccine protection with effective long-term immunity, if at all. mRNA-based vaccines currently used for the COVID-19 outbreak are worrisome. RNA viruses, particularly Coronavirus species, have the peculiar ability to proofread in the viral replication cycle. A correcting enzyme that diminishes the number of mutations can switch the proofreading mechanisms on or off depending on the context, allowing them to rapidly adapt to new environments without losing replicative fidelity. This proofreading ability can short circuit vaccine mRNA’s intended effect in stimulating a reliable immune response against the viral replicating machinery.

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John Catanzaro

John A. Catanzaro is CEO of Neo7logix, a bioscience company that designs precision and personalized treatment designs. www.neo7logix.com